Dear organic chemistry peeps – today I am telling you the tale of the Ginkgo tree and dissect three different total syntheses of Bilobalide, a potential “anti-almost …
Organic Chemistry Explained: Total Synthesis of Anti-Cancer Ginkgo Tree Molecule Bilobalide (Corey)
Dear organic chemistry peeps – today I am telling you the tale of the Ginkgo tree and dissect three different total syntheses of Bilobalide, a potential “anti-almost …
Hey, mate, I was wondering if you can do a video about bio compositions, which can increase life span? Prevent aging maybe?
Thank you for your amazing work!
I would really love to see Vanderwal's strychnine synthesis covered next because of it's sheer efficiency
More more more !❤️
idk if i'd call swapping H2O2 to mCPBZ as luck, wasn't it a common reagent by then?
also 22:37 looks strange. in the molecule, the OBz is gamma to the ester while in the model you draw, it is only beta. am i missing something here?
also, my favorite part of the syntheses has got to be the stereoelectronic discrimination between various hydroxyls, epoxides, and alkenes. really great lessons to be learned, especially for the synth of highly oxidized polycycles. nice presentation
I'm a master student and could not understand a lot of steps 😑. total synthesis is quite hard. thanx for uploading. looking forward to watch new interesting a bit detailed videos 😊
Thank you……its awesome..
Very useful for Total synthesist… Try to do more videos
I've been telling people I couldn't find any channels like mine, yet here you are, doing it better. Cheers!
Amazing work! Congrats
Excellent video! Subscribed.
Love that [2+2] addition to set up that clutch Bayer-Villager later. I got hyped when I saw that ketone installed, idk why, but I just love Bayer-Villagers, and [2+2]'s are probably my favorite cycloaddition.
I'll actually be taking my first real foray into organic synthesis this semester with my second research rotation for my PhD, and your videos have helped out a lot in making synthesis accessible, cause lord knows they try to bore you to death with their papers, lol.
(also, it's probably not really up your alley, but it'd be sick if you ever did a video on the use of biocatalysis in organic synthesis, cause that shit is my jam)
Awesome video. Bilobalide "made easy explanation"! For future videos I would like to see the evolution of total synthesis of Taxol with at least three examples showing the time diferences in state of the art of TotSyn of this historic molecule.
THE KING HAS RETURNED!
I'm so happy you are back
I love the style of these videos.
On another note, do you watch Synthesis Workshop?
And after a year, the Legend returned!
Just woke up and saw that you uploaded, immediately dropped everything and watched it.
Also hello /sci/bros.
ginkgo is the most based tree
psychedelics, or better known as the gateway drugs to organic chemistry.
Great work glad you're back
Awesome video, keep it up mate!
Finally u r back mate, keep it up 😊
BASED SHILLING ON 4CHAN
Finally you’re back! Great work!
Am normie
Great that you're back !
nice
Dude! Missed your videos, great content as always. Keep synthesizing👌🏼
Very interesting video! I have tried Ginkgo Biloba supplements before, but didn’t notice an effect from them. It’s always good to know the chemistry behind what you’re putting in your body lol.
Subscribing Normie reporting in
So happy you're back!!!
Algorithm comment
Shockingly, just 10% of my viewers are subscribed – so please subscribe if you are interested in more videos!
What topics and level of difficulty would you like to see in future videos?
Until next time!
First. Nice work 😉👍